Social approach-avoidance behavior of inbred mouse strains towards DBA/2 mice

被引：136

作者：

Brodkin, ES

Hagemann, A

Nemetski, SM

Silver, LM

机构：

[1] Univ Penn, Sch Med, Ctr Neurobiol & Behav, Dept Psychiat, Philadelphia, PA 19104 USA

[2] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA

来源：

BRAIN RESEARCH | 2004年 / 1002卷 / 1-2期

关键词：

social; behavior; affiliation; approach; avoidance; inbred strain; genetic;

D O I：

10.1016/j.brainres.2003.12.013

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Little is known about the genetics of social approach-avoidance behaviors. We measured social approach-avoidance of prepubescent female C57BL/6J, DBA/2J, FVB/NJ, AKR/J, A/J, and BALB/cJ mice towards prepubescent DBA/2J female mice. C57BL/6J mice showed the greatest predominance of approach, while BALB/cJ mice showed the greatest predominance of avoidance. Thus, this phenotype is affected by spontaneous genetic variation in mice and can be measured in an assay useful for future neurogenetic studies. (C) 2004 Elsevier B.V All rights reserved.

引用

收藏

页码：151 / 157

页数：7

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