Chemo-enzymatic preparation of optically active endo-bicyclo[4.1.0]heptan-2-ols

被引：15

作者：

Barnier, JP ^{[1
]}

Morisson, V ^{[1
]}

Volle, I ^{[1
]}

Blanco, L ^{[1
]}

机构：

[1] Univ Paris Sud, Inst Chim Mol Orsay, Lab Carbocycles, CNRS, F-91405 Orsay, France

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 06期

关键词：

D O I：

10.1016/S0957-4166(99)00099-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Resolutions of endo-bicyclo[4.1.0]heptan-2-ols were achieved by acylation in the presence of lipase from Candida antarctica (Novozym(R)). The (1S,2R,6R) enantiomers reacted faster and the enantiomeric ratios were between 60 and 800 for the 6-substituted bicycloalkanols. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：1107 / 1117

页数：11

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