Innate lymphoid cells - how did we miss them?

被引：530

作者：

Walker, Jennifer A. ^{[1
]}

Barlow, Jillian L. ^{[1
]}

McKenzie, Andrew N. J. ^{[1
]}

机构：

[1] MRC, Mol Biol Lab, Cambridge CB2 0QH, England

来源：

NATURE REVIEWS IMMUNOLOGY | 2013年 / 13卷 / 02期

关键词：

NATURAL-KILLER-CELLS; ROR-GAMMA-T; TISSUE-INDUCER CELLS; TRANSCRIPTION FACTOR GATA3; IFN-GAMMA; INTESTINAL HOMEOSTASIS; ULCERATIVE-COLITIS; TH2; RESPONSES; HELPER-CELLS; RECEPTOR;

D O I：

10.1038/nri3349

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Innate lymphoid cells (ILCs) are newly identified members of the lymphoid lineage that have emerging roles in mediating immune responses and in regulating tissue homeostasis and inflammation. Here, we review the developmental relationships between the various ILC lineages that have been identified to date and summarize their functions in protective immunity to infection and their pathological roles in allergic and autoimmune diseases.

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页码：75 / 87

页数：13

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