Unleashing the power of p53: lessons from mice and men

被引：93

作者：

Poyurovsky, MV ^{[1
]}

Prives, C ^{[1
]}

机构：

[1] Columbia Univ, Dept Biol Sci, New York, NY 10027 USA

来源：

GENES & DEVELOPMENT | 2006年 / 20卷 / 02期

关键词：

D O I：

10.1101/gad.1397506

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

[No abstract available]

引用

页码：125 / 131

页数：7

共 56 条

[1] Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream [J].

Arkin, MR ;

Wells, JA .

NATURE REVIEWS DRUG DISCOVERY, 2004, 3 (04) :301-317

[2] A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells [J].

Arva, NC ;

Gopen, TR ;

Talbott, KE ;

Campbell, LE ;

Chicas, A ;

White, DE ;

Bond, GL ;

Levine, AJ ;

Bargonetti, J .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (29) :26776-26787

[3] SUPPRESSION OF HUMAN COLORECTAL-CARCINOMA CELL-GROWTH BY WILD-TYPE-P53 [J].

BAKER, SJ ;

MARKOWITZ, S ;

FEARON, ER ;

WILLSON, JKV ;

VOGELSTEIN, B .

SCIENCE, 1990, 249 (4971) :912-915

[4] A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans [J].

Bond, GL ;

Hu, WW ;

Bond, EE ;

Robins, H ;

Lutzker, SG ;

Arva, NC ;

Bargonetti, J ;

Bartel, F ;

Taubert, H ;

Wuerl, P ;

Onel, K ;

Yip, L ;

Hwang, SJ ;

Strong, LC ;

Lozano, G ;

Levine, AJ .

CELL, 2004, 119 (05) :591-602

[5] Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo [J].

Bottger, A ;

Bottger, V ;

Sparks, A ;

Liu, WL ;

Howard, SF ;

Lane, DP .

CURRENT BIOLOGY, 1997, 7 (11) :860-869

[6]

Bottger V, 1996, ONCOGENE, V13, P2141

[7] p53 isoforms can regulate p53 transcriptional activity [J].

Bourdon, JC ;

Fernandes, K ;

Murray-Zmijewski, F ;

Liu, G ;

Diot, A ;

Xirodimas, DP ;

Saville, MK ;

Lane, DP .

GENES & DEVELOPMENT, 2005, 19 (18) :2122-2137

[8] Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors [J].

Campisi, J .

CELL, 2005, 120 (04) :513-522

[9] ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage [J].

Chen, LH ;

Gilkes, DM ;

Pan, Y ;

Lane, WS ;

Chen, JD .

EMBO JOURNAL, 2005, 24 (19) :3411-3422

[10]

CORDONCARDO C, 1994, CANCER RES, V54, P794

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