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16-hydroxylated withanolides from Exodeconus maritimus

被引：19
作者：
Gil, RR
Misico, RI
Sotes, IR
Oberti, JC
Veleiro, AS
Burton, G
机构：
[1] UNIV NACL CORDOBA,DEPT QUIM ORGAN,RA-5000 CORDOBA,ARGENTINA
[2] UNIV BUENOS AIRES,FAC CIENCIAS EXACTAS & NAT,DEPT QUIM ORGAN,RA-1428 BUENOS AIRES,DF,ARGENTINA
[3] UNIV NACL CORDOBA,FAC CIENCIAS QUIM,IMBIV,RA-5000 CORDOBA,ARGENTINA
来源：
JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 06期
关键词：
D O I：
10.1021/np970048z
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
In addition to the known compounds withanolide A (4), withanone (5), and NIC-3 (6), three 16-hydroxylated withanolides were isolated from Exodeconus maritimus. The new withanolides were identified as 6 alpha,7 alpha-epoxy-5 alpha,16 beta-dihydroxy-1-oxowitha-2,17(20),24-trienolide (exodeconolide A, 1), 6 alpha,7 alpha-epoxy-5 alpha,16 alpha-dihydroxy-1-oxowitha-2,17(20),24-trienolide (exodeconolide B, 2), and 6 alpha,7 alpha-epoxy-5 alpha,16 alpha,17 alpha-trihydroxy-1-oxowitha-2,24-dienolide (exodeconolide C, 3), by a combination of spectroscopic (1D and 2D NMR, MS) and chemical methods with the aid of molecular modeling.
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收藏
页码：568 / 572
页数：5
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