A new attachment/cleavage strategy: Polymer-bound allylic sulfones in a solid-phase route to trisubstituted olefins

被引：44

作者：

Halm, C ^{[1
]}

Evarts, J ^{[1
]}

Kurth, MJ ^{[1
]}

机构：

[1] UNIV CALIF DAVIS,DEPT CHEM,DAVIS,CA 95616

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(97)10062-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By tethering allyl sulfone to polystyrene (3-steps from polystyrene beads consisting of lithiation, sulfination, and allylation), trisubstituted olefins can be generated by C alpha-sulfone alkylation and subsequent resin cleavage by S(N)2' nucleophilic displacement of sulfinate. (C) 1997 Elsevier Science Ltd.

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收藏

页码：7709 / 7712

页数：4

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