Statistical methods for the analysis and presentation of the results of bone marrow transplants. Part 2: Regression modeling

被引:170
作者
Klein, JP
Rizzo, JD
Zhang, MJ
Keiding, N
机构
[1] Med Coll Wisconsin, Div Biostat, Milwaukee, WI 53226 USA
[2] ABMTR, IBMTR, Milwaukee, WI USA
[3] Univ Copenhagen, Dept Biostat, DK-1168 Copenhagen, Denmark
关键词
Cox model; proportional hazards models; fixed and time-dependent covariate;
D O I
10.1038/sj.bmt.1703271
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
In this paper, we address methods of multivariate regression. We discuss the value of regression compared to matched pairs analysis, methods of coding variables, basic concepts of the Cox model and interpretation of results of the Cox model. We present methods of handling variables whose effect changes with time. We present methods to check the assumptions of the Cox regression. Finally, and perhaps most importantly, we provide suggestions for presenting the results in clear and thorough tables and graphs.
引用
收藏
页码:1001 / 1011
页数:11
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