Interval double transfer improves treatment success in patients with repeated IVF/ET failures

被引:34
作者
Almog, B. [1 ]
Levin, I. [2 ]
Wagman, I. [1 ]
Kapustiansky, R. [1 ]
Schwartz, T. [1 ]
Mey-Raz, N. [1 ]
Amit, A. [1 ]
Azem, F. [1 ]
机构
[1] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Sarah Racine IVF Unit, Lis Matern Hosp, IL-64239 Tel Aviv, Israel
[2] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Lis Matern Hosp, Sackler Fac Med,Dept Gynecol, IL-64239 Tel Aviv, Israel
关键词
Interval double-transfer; Repeated IVF /ET failures;
D O I
10.1007/s10815-008-9237-y
中图分类号
Q3 [遗传学];
学科分类号
071007 [遗传学]; 090102 [作物遗传育种];
摘要
Purpose To examine whether double transfer of embryos on day 2-3 and on day 5 after ovum pick-up (OPU) improves IVF/ET success rates in patients with multiple consecutive IVF failures Methods Consecutive IVF failures patients (7.6 +/- 0.5) undergoing IVF/ET cycles were treated with interval double transfer on day 2-3 and on day 5 after OPU. Matched patients, that had embryos transferred only once on day 2 or 3 served as controls. Results Baseline and cycle characteristics were similar in the study group and controls. The total pregnancy rate was 44.6% in the study group and 24.2% in the controls (p=0.001), and the clinical pregnancy rates were 38.5% and 19.6%, respectively (p=0.001). Conclusions Patients with multiple consecutive IVF/ET failures, treated with the interval double transfer approach had significantly improved cycle success rates compared with regular day 2 or 3 embryo transfer protocol.
引用
收藏
页码:353 / 357
页数:5
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