Antioxidant properties of nitrocaffeic acids

被引：11

作者：

Grenier, JL ^{[1
]}

Cotelle, N ^{[1
]}

Cotelle, P ^{[1
]}

Catteau, JP ^{[1
]}

机构：

[1] UNIV SCI & TECH LILLE FLANDRES ARTOIS,CHIM PHYS ORGAN LAB,URA CNRS 351,F-59655 VILLENEUVE DASCQ,FRANCE

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 04期

关键词：

D O I：

10.1016/0960-894X(96)00048-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of nitrodihydroxybenzenes and nitrocaffeic acids were prepared and their hydroxyl radical (OH degrees) and superoxide anion (O-2(-)) scavenging activities and xanthine oxidase inhibition activities were evaluated. 2-Nitrocaffeic acid is the more potent O-2(-) scavenger. 2-(and 5)-Nitrocaffeic acids are the more potent xanthine oxidase inhibitors.

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收藏

页码：431 / 434

页数：4

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