How the gene content of human sex chromosomes evolved

被引：45

作者：

Graves, Jennifer A. Marshall ^{[1
]}

Koina, Edda

SankoviC, Natasha

机构：

[1] Australian Natl Univ, Res Sch Biol Sci, Canberra, ACT, Australia

[2] Univ Melbourne, Dept Zool, Melbourne, Vic, Australia

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2006年 / 16卷 / 03期

基金：

澳大利亚研究理事会;

关键词：

D O I：

10.1016/j.gde.2006.04.007

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The X and Y chromosomes of humans and other mammals both have very atypical gene contents. The degenerate Y bears only a handful of genes that are specialized for male sex and reproduction. Now it seems that the X over-represents genes controlling reproductive traits and intelligence. This is hard to explain in terms of function but makes excellent sense in terms of evolution. Comparisons between the gene content of the X and Y in humans, distantly related mammals, and other vertebrates, define the evolutionary past of our sex chromosomes and suggest how special selective forces act on the X and Y.

引用

页码：219 / 224

页数：6

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