Gas-liquid chromatography mass spectrometry of primary and secondary fatty alcohols and diols as their tert.-butyldimethylsilyl derivatives

被引：8

作者：

Chance, DL

Gerhardt, KO

Mawhinney, TP

机构：

[1] UNIV MISSOURI,DEPT BIOCHEM,COLUMBIA,MO 65211

[2] UNIV MISSOURI,DEPT CHILD HLTH,COLUMBIA,MO 65211

来源：

JOURNAL OF CHROMATOGRAPHY A | 1997年 / 771卷 / 1-2期

关键词：

derivatization; GC; fatty alcohols; lipids; diols; alcohol;

D O I：

10.1016/S0021-9673(97)00197-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The use of gas-liquid chromatography (GLC) and mass spectrometry (MS) with derivatizing agents which give stable derivatives and informative fragmentation patterns allows for accurate identification of a variety of compounds. In this comprehensive study, the tert.-butyldimethylsilyl (tBDMS) derivatives of saturated and unsaturated primary alcohols, iso and anteiso-primary alcohols, branched alcohols, secondary alcohols and primary diols were produced and analyzed by GLC-MS. Most derivatized alcohols produced prominent mass minus 57 [M-57](+) fragment ions, which, combined with their respective retention data and other key fragment ions, allows for their identification and analysis.

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页码：191 / 201

页数：11

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