2-methyl N-(p-toluenesulfinyl)aziridine-2-carboxylic acid: Asymmetric synthesis of alpha-methylphenylalanine and alpha-methyl-beta-phenylserine

被引：87

作者：

Davis, FA

Liu, H

Reddy, GV

机构：

[1] Department of Chemistry, Temple University, Philadelphia

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 31期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0040-4039(96)01168-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Substituted aziridine 2a, prepared from sulfinimine 1 via a Darzens-type condensation, undergoes a highly regio- and stereocontrolled ring-opening to give alpha-methylphenylalanine and alpha-methyl-beta-phenylserine in high enantiomeric purity. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：5473 / 5476

页数：4

共 40 条

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