Auditory evoked potential abnormalities in cluster headache

被引:12
作者
Casale, Malcolm S. [2 ,3 ]
Baratto, Marta [4 ]
Cervera, Christina [4 ]
Gallamini, Michele [4 ]
Lynch, Gary [2 ]
Gjini, Klevest [1 ]
Boutros, Nash N. [1 ]
机构
[1] Wayne State Univ, Sch Med, Dept Psychiat & Biobehav Neurosci, UPC Jefferson, Detroit, MI 48207 USA
[2] Univ Calif Irvine, Dept Psychiat & Human Behav, Irvine, CA 92717 USA
[3] Thuris Corp, Irvine, CA USA
[4] RGM SpA, Med Device Div, Genoa, Italy
关键词
cluster headache; event-related potentials; N100; P200; P300;
D O I
10.1097/WNR.0b013e328314e0dd
中图分类号
Q189 [神经科学];
学科分类号
071006 [神经生物学];
摘要
Mid-latency and long-latency auditory evoked responses were investigated in 27 patients with cluster headache who had a mean age of 38.7 +/- 9.7 years and who were free of pain at the time of testing. Twenty-five age-matched healthy persons served as controls. Latencies and amplitudes of corresponding responses (N100, P200, and P300) were measured. The parameters were calculated at P-z for the P300 and C-z electrodes for the N100 and P200. Multiple analysis of variance revealed a significant overall effect of group (P=0.011). P200 amplitude was significantly smaller in cluster headache patients (P=0.0002). No differences were found for N100 or P300. These data suggest a hitherto unrecognized defect in the information processing pathways, in the early attentive phase represented by the P200 component. NeuroReport 19:1633-1636 (C) 2008 Wolters Kluwer Health Lippincott Williams & Wilkins.
引用
收藏
页码:1633 / 1636
页数:4
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