The use of desorption/ionization on porous silicon mass spectrometry for the detection of negative ions for fatty acids

被引:38
作者
Budimir, N [1 ]
Blais, JC [1 ]
Fournier, F [1 ]
Tabet, JC [1 ]
机构
[1] Univ Paris 06, Equipe Spectrometr Massee, LCSOB, CNRS,UMR 7613, F-75252 Paris, France
关键词
D O I
10.1002/rcm.2363
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The study of low molecular weight compounds by matrix-assisted laser desorption/ionization (MALDI) is difficult because of the presence of ions originating from the matrix in the low-m/z range. In order to resolve these problems, new matrix-free approaches were developed based on laser desorption/ionization from the surface of various materials such as graphite and porous silicon. Our work involves the use of 'desorption ionization on porous silicon mass spectrometry' (DIOS-MS) in the negative ion mode to study fatty acid compounds. The potential of the DIOS-MS technique is shown and an insight into the ionization mechanism provided. Copyright (c) 2006 John Wiley & Sons, Ltd.
引用
收藏
页码:680 / 684
页数:5
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