A comparison of screening tools for the assessment of Mild Cognitive Impairment: Preliminary findings

被引:47
作者
Ahmed, Samrah [1 ]
de Jager, Celeste [1 ]
Wilcock, Gordon [1 ]
机构
[1] Univ Oxford, Nuffield Dept Med Anat & Genet, Oxford Project Invest Memory & Ageing OPTIMA, Oxford, England
关键词
Neuropsychological assessment; Dementia; Mild Cognitive Impairment; Diagnosis; MINI-MENTAL-STATE; EARLY ALZHEIMERS-DISEASE; SEMANTIC MEMORY; TEST BATTERY; NEUROPSYCHOLOGICAL TESTS; FRONTOTEMPORAL DEMENTIA; EARLY-DIAGNOSIS; EXAMINATION ACE; LEWY BODIES; CUED-RECALL;
D O I
10.1080/13554794.2011.608365
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
We report a pilot investigation into the utility of screening tools in Mild Cognitive Impairment (MCI). The Addenbrooke's Cognitive Examination-Revised (ACE-R), Montreal Cognitive Assessment (MoCA) and the novel Computer-Administered Neuropsychological Screen for Mild Cognitive Impairment (CANS-MCI) were administered to 20 elderly controls and 15 MCI cases. Non-parametric Mann-Whitney U-tests showed significant differences between groups (p < .0001) on the CANS-MCI and MoCA. The ACE-R and MoCA total scores showed high sensitivity (90%) to MCI. Area under the curve was consistently significant in discriminating controls and MCI for memory scores across all screening instruments. A useful profile of quantitative and qualitative information pertaining to cognitive functioning in MCI can be obtained with the MoCA, ACE-R, and CANS-MCI.
引用
收藏
页码:336 / 351
页数:16
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