Inflammatory pseudotumors of the pancreas and liver with infiltration of IgG4-positive plasma cells

被引:32
作者
Uchida, Kazushige [1 ]
Satoi, Sohei [2 ]
Miyoshi, Hideaki [1 ]
Hachimine, Daisaku [1 ]
Ikeura, Tsukasa [1 ]
Shimatani, Masaaki [1 ]
Matsushita, Mitsunobu [1 ]
Takaoka, Makoto [1 ]
Takai, Soichiro [2 ]
Ashida, Kiyoshi [3 ]
Okazaki, Kazuichi [1 ]
机构
[1] Kansai Med Univ, Dept Internal Med 3, Moriguchi, Osaka 570, Japan
[2] Kansai Med Univ, Dept Surg, Hirakata, Osaka, Japan
[3] Osaka Saiseikai Nakatsu Hosp, Dept Gastroenterol, Osaka, Japan
关键词
autoimmune pancreatitis; inflammatory pseudotumor; pancreatic cancer;
D O I
10.2169/internalmedicine.46.6430
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recently, it has been reported that autoimmune pancreatitis (AIP) can be complicated with various extra-pancreatic lesions. Here, we report a very rare case of pancreatic and hepatic inflammatory pseudotumor (IPT) with the infiltration of IgG4-positive plasmacytes. The patient showed pancreatic and hepatic masses with elevated levels of serum IgG4. Endoscopic retrograde cholangiopancreatography revealed narrowing of the intrapancreatic bile duct. Fluorine-18fluorodeoxyglucose positron emission tomography suggested pancreatic cancer with hepatic metastasis. Histopathologic findings showed fibrosis and infiltration of IgG4-positive plasmacytes, suggesting IPT. The present case suggests a possible common mechanism in the development of AIP and IPT of the liver.
引用
收藏
页码:1409 / 1412
页数:4
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