Interassay differences in growth hormone measurement in acromegaly

被引：3

作者：

Barth, JH ^{[1
]}

Smith, JH ^{[1
]}

Clarkson, P ^{[1
]}

机构：

[1] PINDERFIELDS GEN HOSP, DEPT CHEM PATHOL, WAKEFIELD, W YORKSHIRE, ENGLAND

来源：

ANNALS OF CLINICAL BIOCHEMISTRY | 1997年 / 34卷

关键词：

immunometric assays; isoforms;

D O I：

10.1177/000456329703400204

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

We measured plasma growth hormone concentrations by three different two-site immunometric assays (Pharmacia hGH RIA, IDS Gamma-BCT and Delfia 22 kDa hGH) to determine whether there are GH isoforms secreted by acromegalic patients that are under-recognized by some assays. There was a fairly good agreement between assays with the IDS Gamma-BCT and Delfia 22 kDa assays giving lower results than the Pharmacia IRMA. GH was measured on stored plasma samples from 24 patients with proven acromegaly. There was a consistent difference between the three assays of approximately 20% of the mean value for each patient.

引用

页码：156 / 159

页数：4

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