Role of Bcl-2 family members in immunity and disease

被引：53

作者：

Droin, NM ^{[1
]}

Green, DR ^{[1
]}

机构：

[1] La Jolla Inst Allergy & Immunol, Div Cellular Immunol, San Diego, CA 92121 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | 2004年 / 1644卷 / 2-3期

关键词：

apoptosis; Bcl-2; BH3-only protein; regulation; disease; immunity;

D O I：

10.1016/j.bbamcr.2003.10.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The different members of the Bcl-2 family are essential regulators of programmed cell death. These different members share one or more Bcl-2 homology domains, required for their ability to regulate each other. In this review, we describe current knowledge of the functions of different Bcl-2 members and their potential roles in disease and immunity. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：179 / 188

页数：10

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