Cross-metathesis assisted by microwave irradiation

被引：49

作者：

Bargiggia, FC ^{[1
]}

Murray, WV ^{[1
]}

机构：

[1] Johnson & Johnson Pharmaceut Res & Dev, LLC, Raritan, NJ 08869 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 23期

关键词：

D O I：

10.1021/jo0514624

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Microwave irradiation effectively accelerates cross-coupling metathesis reactions between deactivated olefins. Reactions have been carried out with the phosphine-free Hoveyda-Grubbs catalyst and the "second generation Grubbs' catalyst." While there have been reports that a "microwave effect" is observed in various transformations, the accelerations we observe are due to the efficient and rapid heating and increased pressure in the microwave apparatus.

引用

页码：9636 / 9639

页数：4

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