Cardiac biomarkers: a contemporary status report

被引：68

作者：

Maisel, AS

Bhalla, V

Braunwald, E

机构：

[1] VASDHS, Coronary Care Unit, La Jolla, CA 92161 USA

[2] Univ Calif San Diego, San Diego, CA 92103 USA

[3] Harvard Univ, Sch Med, Brigham & Womens Hosp, Boston, MA 02115 USA

来源：

NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE | 2006年 / 3卷 / 01期

关键词：

acute coronary syndromes; biomarker-guided therapy; cardiac biomarkers; inflammatory biomarkers; multimarker strategies;

D O I：

10.1038/ncpcardio0405

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The field of cardiac biomarkers has grown by leaps and bounds in the past two decades. In this review we try to summarize the explosion of emerging knowledge and address the roles of some of the biomarkers that have either proven or potential utility. We detail some of the markers of ischemia, hemodynamic markers of heart failure, inflammatory markers, and the novel and innovative approach of combining these for a multimarker strategy. At the end of this review we highlight some of the biomarker-guided approaches and strategies that might lead to better and more-effective care of patients.

引用

页码：24 / 34

页数：11

共 68 条

[1] DIAGNOSIS OF PERIOPERATIVE MYOCARDIAL-INFARCTION WITH MEASUREMENT OF CARDIAC TROPONIN-I [J].

ADAMS, JE ;

SICARD, GA ;

ALLEN, BT ;

BRIDWELL, KH ;

LENKE, LG ;

DAVILAROMAN, VG ;

BODOR, GS ;

LADENSON, JH ;

JAFFE, AS .

NEW ENGLAND JOURNAL OF MEDICINE, 1994, 330 (10) :670-674

[2] Myocardial infarction redefined -: A consensus Document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction [J].

Alpert, JS ;

Antman, E ;

Apple, F ;

Armstrong, PW ;

Bassand, JP ;

de Luna, AB ;

Beller, G ;

Breithardt, G ;

Chaitman, BR ;

Clemmensen, P ;

Falk, E ;

Fishbein, MC ;

Galvani, M ;

Garson, A ;

Grines, C ;

Hamm, C ;

Jaffe, A ;

Katus, H ;

Kjekshus, J ;

Klein, W ;

Klootwijk, P ;

Lenfant, C ;

Levy, D ;

Levy, RI ;

Luepker, R ;

Marcus, F ;

Näslund, U ;

Ohman, M ;

Pahlm, O ;

Poole-Wilson, P ;

Popp, R ;

Alto, P ;

Pyörälä, K ;

Ravkilde, J ;

Rehnquist, N ;

Roberts, W ;

Roberts, R ;

Roelandt, J ;

Rydén, L ;

Sans, S ;

Simoons, ML ;

Thygesen, K ;

Tunstall-Pedoe, H ;

Underwood, R ;

Uretsky, BF ;

Van de Werf, F ;

Voipio-Pulkki, LM ;

Wagner, G ;

Wallentin, L ;

Wijns, W .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (03) :959-969

[3]

*AM HEART ASS, 2002, HEART DIS STROK STAT

[4] Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes [J].

Antman, EM ;

Tanasijevic, MJ ;

Thompson, B ;

Schactman, M ;

McCabe, CH ;

Cannon, CP ;

Fischer, GA ;

Fung, AY ;

Thompson, C ;

Wybenga, D ;

Braunwald, E .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (18) :1342-1349

[5]

Anzai T, 1997, CIRCULATION, V96, P778

[6] RELATIONSHIP BETWEEN PLASMA-LEVEL OF BRAIN NATRIURETIC PEPTIDE AND MYOCARDIAL INFARCT SIZE [J].

ARAKAWA, N ;

NAKAMURA, M ;

AOKI, H ;

HIRAMORI, K .

CARDIOLOGY, 1994, 85 (05) :334-340

[7] A prospective study in search of an optimal B-natriuretic peptide level to screen patients for cardiac dysfunction [J].

Atisha, D ;

Bhalla, MA ;

Morrison, LK ;

Felicio, L ;

Clopton, P ;

Gardetto, N ;

Kazanegra, R ;

Chiu, A ;

Maisel, AS .

AMERICAN HEART JOURNAL, 2004, 148 (03) :518-523

[8] Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes [J].

Baldus, S ;

Heeschen, C ;

Meinertz, T ;

Zeiher, AM ;

Eiserich, JP ;

Münzel, T ;

Simoons, ML ;

Hamm, CW .

CIRCULATION, 2003, 108 (12) :1440-1445

[9] Reduced albumin-cobalt binding with transient myocardial ischemia after elective percutaneous transluminal coronary angioplasty: A preliminary comparison to creatine kinase-MB, myoglobin, and troponin I [J].

Bar-Or, D ;

Winkler, JV ;

VanBenthuysen, K ;

Harris, L ;

Lau, E ;

Hetzel, FW .

AMERICAN HEART JOURNAL, 2001, 141 (06) :985-991

[10] B-type natriuretic peptide: a novel early blood marker of acute myocardial infarction in patients with chest pain and no ST segment elevation [J].

Bassan, R ;

Potsch, A ;

Maisel, A ;

Tura, B ;

Villacorta, H ;

Nogueira, MV ;

Campos, A ;

Gamarski, R ;

Masetto, AC ;

Moutinho, MA .

EUROPEAN HEART JOURNAL, 2005, 26 (03) :234-240

← 1 2 3 4 5 6 7 →