Long-Term Mortality Rates in Acute De Novo Versus Acute-on-Chronic Heart Failure: From the Heart Function Assessment Registry Trial in Saudi Arabia

被引:22
作者
AlHabib, Khalid F. [1 ]
Kashour, Tarek [1 ]
Elasfar, Abdelfatah A. [2 ,3 ]
Alfaleh, Hussam [1 ]
Hersi, Ahmad [1 ]
Alshamiri, Mostafa [1 ]
Alshaer, Fayez [1 ]
Mimish, Layth [4 ]
Almasood, Ali [5 ]
AlHabeeb, Waleed [1 ,6 ]
AlGhamdi, Saleh [7 ]
Ghabashi, Abdullah [8 ]
Asfina, KaziNur [1 ]
Altaradi, Hani [1 ]
Alnobani, Omar [1 ]
Alkamel, Nour [1 ]
Thalib, Lukman [9 ]
机构
[1] King Saud Univ, Coll Med, King Fahad Cardiac Ctr, Dept Cardiac Sci, Riyadh 11472, Saudi Arabia
[2] King Fahd Med City, Prince Salman Heart Ctr, Riyadh, Saudi Arabia
[3] Tanta Univ, Dept Cardiol, Tanta, Egypt
[4] King Abdulaziz Univ Hosp, Jeddah, Saudi Arabia
[5] Prince Sultan Cardiac Ctr, Riyadh, Saudi Arabia
[6] King Faisal Specialist Hosp & Res Ctr, King Faisal Cardiac Ctr, Riyadh, Saudi Arabia
[7] Madina Cardiac Ctr, Al Madina Al Monaoarah, Saudi Arabia
[8] Prince Sultan Cardiac Ctr, Hafouf, Saudi Arabia
[9] Kuwait Univ, Fac Med, Hlth Sci Ctr, Kuwait, Kuwait
关键词
acute heart failure; Saudi Arabia; middle east; HEARTS; registry; EUROBSERVATIONAL RESEARCH-PROGRAM; TASK-FORCE; EUROPEAN-SOCIETY; OUTCOMES; ASSOCIATION; ESC; PREDICTORS; COLLABORATION; GUIDELINES; MANAGEMENT;
D O I
10.1177/0003319714563138
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Aim: The heart function assessment registry trial in Saudi Arabia (HEARTS) is a national multicenter project that compared de novo versus acute-on-chronic heart failure (ACHF). Methods and Results: This is a prospective registry in 18 hospitals in Saudi Arabia between October 2009 and December 2010. The study enrolled 2610 patients: 940 (36%) de novo and 1670 (64%) ACHF. Patients with ACHF were significantly older (62.2 vs 60 years), less likely to be males (64% vs 69%) or smokers (31.6% vs 36.7%), and more likely to have history of diabetes mellitus (65.7% vs 61.3%), hypertension (74% vs 65%), and severe left ventricular dysfunction (52% vs 40%). The ACHF group had a higher adjusted 3-year mortality rate (hazard ratio, 1.6; 95% confidence interval [CI] 1.3-2.0; P < .001). Conclusion: Patients with ACHF had significantly higher long-term mortality rates than those with de novo acute heart failure (HF). Multidisciplinary HF disease management programs are highly needed for such high-risk populations.
引用
收藏
页码:837 / 844
页数:8
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