Implications of the human microbiome in inflammatory bowel diseases

被引：57

作者：

Bakhtiar, Syeda M. ^{[1
]}

Guy LeBlanc, Jean ^{[2
,3
]}

Salvucci, Emiliano ^{[4
]}

Ali, Amjad ^{[1
]}

Martin, Rebeca ^{[5
,6
]}

Langella, Philippe ^{[5
,6
]}

Chatel, Jean-Marc ^{[5
,6
]}

Miyoshi, Anderson ^{[1
]}

Bermudez-Humaran, Luis G. ^{[5
,6
]}

Azevedo, Vasco ^{[1
]}

机构：

[1] Univ Fed Minas Gerais, ICB, Belo Horizonte, MG, Brazil

[2] Consejo Nacl Invest Cient & Tecn, Ctr Referencia Lactobacilos CERELA, San Miguel De Tucuman, Tucuman, Argentina

[3] Univ Nacl Tucuman, Fac Med, Catedra Metodol Invest Cient, RA-4000 San Miguel De Tucuman, Tucuman, Argentina

[4] Univ Nacl Cordoba, Inst Ciencia & Tecnol Alimentos, Fac Ciencias Exactas Fis & Nat, RA-5000 Cordoba, Argentina

[5] INRA, Micalis UMR1319, Commensal & Probiot Host Interact Lab, F-78352 Jouy En Josas, France

[6] AgroParisTech, Micalis UMR1319, Jouy En Josas, France

来源：

FEMS MICROBIOLOGY LETTERS | 2013年 / 342卷 / 01期

关键词：

Microbiome; Human holobiont; Microbiota; Commensal; GUT MICROBIOME; INTESTINAL MICROBIOTA; MICROARRAY ANALYSIS; BODY HABITATS; OBESITY; PROBIOTICS; NUTRITION; EVOLUTION; RESPONSES; SYMBIOSIS;

D O I：

10.1111/1574-6968.12111

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

The study of the human microbiome or community of microorganisms and collection of genomes found in the human body is one of the fastest growing research areas because many diseases are reported to be associated with microbiome imbalance or dysbiosis. With the improvement in novel sequencing techniques, researchers are now generating millions of sequences of different sites from the human body and evaluating specific differences in microbial communities. The importance of microbiome constituency is so relevant that several consortia like the Human Microbiome project (HMP) and Metagenomics of the Human Intestinal Tract (MetaHIT) project are focusing mainly on the human microbiome. The aim of this review is to highlight points of research in this field, mainly focusing on particular factors that modulate the microbiome and important insights into its potential impact on our health and well-being.

引用

页码：10 / 17

页数：8

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