Activated protein C resistance assay when applied in the general population

被引：13

作者：

Altes, A ^{[1
]}

Souto, JC ^{[1
]}

Mateo, J ^{[1
]}

Borrell, M ^{[1
]}

Fontcuberta, J ^{[1
]}

机构：

[1] HOSP ESPERIT SANT,SANT COLOMA GRAMANET,SPAIN

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1997年 / 176卷 / 02期

关键词：

activated protein C resistance; factor V Leiden; thrombosis; oral contraceptives; pregnancy;

D O I：

10.1016/S0002-9378(97)70498-8

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

We estimated the predictive values of activated protein C resistance in the diagnosis of women who are carriers of factor V Leiden. When the prevalence of factor V Leiden is 2%, the positive predictive value is 44% and the cost of preventing one thromboembolic death is $44,180,000. Thus the activated protein C resistance assay is not cost-effective in ruling out factor V Leiden in this population.

引用

页码：358 / 359

页数：2