Developing a taste for sweets

被引:45
作者
Baum, LG [1 ]
机构
[1] Univ Calif Los Angeles, Sch Med, Dept Pathol & Lab Med, Los Angeles, CA 90095 USA
关键词
D O I
10.1016/S1074-7613(02)00265-0
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Lymphocytes are covered with sugars. Some of the oligosaccharides on lymphocytes may be recognized by specific lectins such as the selectins, but what other functions do all of these oligosaccharides serve? Two recent papers in Cell (Moody et al., 2001) and Immunity (Daniels et al., 2001) describe a novel role for glycosylation in the thymus - regulating the interaction of MHC class I molecules with CD8 during thymocyte maturation.
引用
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页码:5 / 8
页数:4
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