Biological clocks

被引:80
作者
Ishida, N
Kaneko, M
Allada, R
机构
[1] Minist Int Trade & Ind, Agcy Ind Sci & Technol, Natl Inst Biosci & Human Technol, Ishida Grp Clock Gene, Tsukuba, Ibaraki 305, Japan
[2] Brandeis Univ, Dept Biol, Waltham, MA 02454 USA
[3] Brandeis Univ, Dept Biol, Natl Sci Fdn, Ctr Biol Timing,Howard Hughes Med Inst, Waltham, MA 02254 USA
[4] Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA
关键词
D O I
10.1073/pnas.96.16.8819
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Circadian rhythms describe biological phenomena that oscillate with an approximate to 24-hour cycle. These rhythms include blood pressure, body temperature, hormone levels, the number of immune cells in blood, and the sleep-wake cycle, In this paper, we will focus on common genes between species that are responsible for determining the circadian behavior, especially some transcription factors (i.e., switch genes) that serve to regulate many circadian rhythm genes. The intent of this summary is to introduce the common molecular mechanism of biological clocks between flies and humans and then to describe the research from three laboratories that was presented in the session.
引用
收藏
页码:8819 / 8820
页数:2
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