Molecular genetic analysis of high-level gentamicin resistance in Enterococcus hirae

被引：15

作者：

Mangan, MW

McNamara, EB

Smyth, EG

Storrs, MJ

机构：

[1] DEPT MICROBIOL, DUBLIN 9, IRELAND

[2] ROYAL COLL SURGEONS IRELAND, DUBLIN 2, IRELAND

[3] BEAUMONT HOSP, DEPT MICROBIOL, DUBLIN 9, IRELAND

[4] REG TECH COLL TALLAGHT, DEPT APPL SCI, DUBLIN 24, IRELAND

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1997年 / 40卷 / 03期

关键词：

D O I：

10.1093/jac/40.3.377

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

High-level resistance to gentamicin was studied in seven clinical isolates of Enterococcus hirae. In common with other members of the genus Enterococcus, such resistance in E. hirae was associated with single, large, conjugative plasmids. Molecular genetic analysis revealed five distinct plasmid types amongst the seven isolates. The determinant mediating high-level gentamicin resistance in E. hirae was also shown to be homologous to that already characterized for other enterococcal species.

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页码：377 / 382

页数：6

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