Brine shrimp lethality essay of Bacopa monnieri

被引：18

作者：

D'Souza, P ^{[1
]}

Deepak, M ^{[1
]}

Rani, P ^{[1
]}

Kadamboor, S ^{[1
]}

Mathew, A ^{[1
]}

Chandrashekar, AP ^{[1
]}

Agarwal, A ^{[1
]}

机构：

[1] MS Nat Remedies Pvt Ltd, Bioassay Unit, Bangalore 561229, Karnataka, India

来源：

PHYTOTHERAPY RESEARCH | 2002年 / 16卷 / 02期

关键词：

Bacopa monnieri; brine shrimp lethality; cytotoxicity; bacoside A;

D O I：

10.1002/ptr.1001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Successive petroleum ether, chloroform, ethanol;and water extracts, a saponin rich fraction (SRF) and bacoside A isolated from Bacopa monnieri were tested for brine shrimp lethality. Successive ethanol extracts and SRF showed potent activity. Bacoside A showed the maximum activity with a LC50 of 38.3 mug/mL. The results confirmed the previous reports of an anticancer effect of Bacopa monnieri and suggest bacoside A as the active constituent. Copyright (C) 2002 John Wiley Sons, Ltd.

引用

页码：197 / 198

页数：2