The role of tea and tea flavonoids in cardiovascular health

被引:184
作者
Stangl, V [1 ]
Lorenz, M [1 ]
Stangl, K [1 ]
机构
[1] Univ Med Berlin, Med Klin, Charite, D-10117 Berlin, Germany
关键词
atherosclerosis; cardiovascular; endothelial function; flavonoids; tea;
D O I
10.1002/mnfr.200500118
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Consumption of green or black tea has been inversely associated with the development and progression of cardiovascular diseases. In this review, the current knowledge about protective effects of tea and tea constituents, particularly flavonoids, on the cardiovascular system is summarized. Underlying mechanisms for the beneficial effects of tea include vasculoprotective, antioxidative, antithrombogenic, anti-inflammatory, and lipid-lowering properties of tea flavonoids. Although promising experimental data on beneficial effects of tea in various cardiovascular diseases are available, results of clinical studies in humans are not uniform. A number of factors are discussed which may contribute to inconsistent data in humans. Overall, tea represents a promising tool for the prevention and treatment of cardiovascular disorders.
引用
收藏
页码:218 / 228
页数:11
相关论文
共 109 条
[1]   EFFECT OF GREEN TEA RICH IN GAMMA-AMINOBUTYRIC-ACID ON BLOOD-PRESSURE OF DAHL SALT-SENSITIVE RATS [J].
ABE, Y ;
UMEMURA, S ;
SUGIMOTO, K ;
HIRAWA, N ;
KATO, Y ;
YOKOYAMA, N ;
YOKOYAMA, T ;
IWAI, J ;
ISHII, M .
AMERICAN JOURNAL OF HYPERTENSION, 1995, 8 (01) :74-79
[2]   Epigallocathechin-3 gallate selectively inhibits the PDGF-BB-induced intracellular signaling transduction pathway in vascular smooth muscle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172) [J].
Ahn, HY ;
Hadizadeh, KR ;
Seul, C ;
Yun, YP ;
Vetter, H ;
Sachinidis, A .
MOLECULAR BIOLOGY OF THE CELL, 1999, 10 (04) :1093-1104
[3]   Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta [J].
Andriambeloson, E ;
Magnier, C ;
Haan-Archipoff, G ;
Lobstein, A ;
Anton, R ;
Beretz, A ;
Stoclet, JC ;
Andriantsitohaina, R .
JOURNAL OF NUTRITION, 1998, 128 (12) :2324-2333
[4]   Epigallocatechin, a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats [J].
Aneja, R ;
Hake, PW ;
Burroughs, TJ ;
Denenberg, AG ;
Wong, HR ;
Zingarelli, B .
MOLECULAR MEDICINE, 2004, 10 (1-6) :55-62
[5]   p38 Mitogen-activated protein kinase activates eNOS in endothelial cells by an estrogen receptor α-dependent pathway in response to black tea polyphenols [J].
Anter, E ;
Chen, K ;
Shapira, OM ;
Karas, RH ;
Keaney, JF .
CIRCULATION RESEARCH, 2005, 96 (10) :1072-1078
[6]   Anti-obesity actions of green tea: Possible involvements in modulation of the glucose uptake system and suppression of the adipogenesis-related transcription factors [J].
Ashida, H ;
Furuyashiki, T ;
Nagayasu, H ;
Bessho, H ;
Sakakibara, H ;
Hashimoto, T ;
Kanazawa, K .
BIOFACTORS, 2004, 22 (1-4) :135-140
[7]   The chemistry of tea flavonoids [J].
Balentine, DA ;
Wiseman, SA ;
Bouwens, LCM .
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 1997, 37 (08) :693-704
[8]  
Beecher GR, 2003, J NUTR, V133, p3248S
[9]   Effect of black tea drinking on blood lipids, blood pressure and aspects of bowel habit [J].
Bingham, SA ;
Vorster, H ;
Jerling, JC ;
Magee, E ;
Mulligan, A ;
Runswick, SA ;
Cummings, JH .
BRITISH JOURNAL OF NUTRITION, 1997, 78 (01) :41-55
[10]  
Cheng TO, 2003, AM J CARDIOL, V91, P1290, DOI [10.1016/S0002-9149(03)00104-8, 10.1016/S0002-9149(03)00103-6]