Pectins and xyloglucans exhibit antimutagenic activities against nitroaromatic compounds

被引：22

作者：

Hensel, A ^{[1
]}

Meier, I ^{[1
]}

机构：

[1] Univ Erlangen Nurnberg, Inst Bot & Pharmazeut Biol, D-91058 Erlangen, Germany

来源：

PLANTA MEDICA | 1999年 / 65卷 / 05期

关键词：

polysaccharides; xyloglucan; pectin; antimutagenicity; Salmonella typhimurium;

D O I：

10.1055/s-1999-14013

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Because a high daily consumption of polysaccharides-containing food is assessed to decrease the risk of cancer of the gastrointestinal system, different types of carbohydrates were investigated for their antimutagenic activity against different standard mutagens. Within the screening pronounced antimutagenic effects were found for xyloglucan and different pectins and pectin-like rhamnogalacturonans against 1-nitropyrene induced mutagenicity. Inhibition rates were dose-dependent and varied between 20 and 50 %. Concerning the mode of action a direct interaction of the polymers with the cells is claimed, protecting the organisms from the mutagenic attack.

引用

页码：395 / 399

页数：5

共 18 条

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