Multiple surface plasmon spectroscopy for study of biomolecular systems

被引：70

作者：

Adam, P ^{[1
]}

Dostálek, J ^{[1
]}

Homola, J ^{[1
]}

机构：

[1] Acad Sci Czech Republ, Inst Radio Engn & Elect, Prague 18251, Czech Republic

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2006年 / 113卷 / 02期

关键词：

surface plasmon; diffraction grating; surface plasmon resonance; sensor;

D O I：

10.1016/j.snb.2005.07.029

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We report a new approach to surface plasmon resonance (SPR) biosensing based on spectroscopy of multiple surface plasmons on a special multi-diffractive grating coupler. In this approach, the binding event at a surface of the SPR grating coupler is simultaneously observed by surface plasmons of different wavelengths, which makes it possible to determine binding-induced changes in the refractive index distribution at the sensor surface. We demonstrate the potential of this new concept in a model experiment in which three-surface plasmon spectroscopy is used to determine background refractive index variations and changes in the thickness and refractive index of a bovine serum albumin multi-layer grown on the surface of the SPR grating coupler. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：774 / 781

页数：8

共 24 条

[1] OPTICAL-PROPERTIES OF THIN-LAYERS OF BOVINE SERUM-ALBUMIN, GAMMA-GLOBULIN, AND HEMOGLOBIN [J].

ARWIN, H .

APPLIED SPECTROSCOPY, 1986, 40 (03) :313-318

[2] OPTICAL-PROPERTIES OF THIN-FILMS [J].

ASPNES, DE .

THIN SOLID FILMS, 1982, 89 (03) :249-262

[3] 3-DIMENSIONAL STRUCTURE OF HUMAN-SERUM ALBUMIN [J].

CARTER, DC ;

HE, XM ;

MUNSON, SH ;

TWIGG, PD ;

GERNERT, KM ;

BROOM, MB ;

MILLER, TY .

SCIENCE, 1989, 244 (4909) :1195-1198

[4] DETERMINATION OF THICKNESS AND DIELECTRIC-CONSTANT OF THIN TRANSPARENT DIELECTRIC LAYERS USING SURFACE-PLASMON RESONANCE [J].

DEBRUIJN, HE ;

ALTENBURG, BSF ;

KOOYMAN, RPH ;

GREVE, J .

OPTICS COMMUNICATIONS, 1991, 82 (5-6) :425-432

[5] Multichannel surface plasmon resonance biosensor with wavelength division multiplexing [J].

Dostálek, J ;

Vaisocherová, H ;

Homola, J .

SENSORS AND ACTUATORS B-CHEMICAL, 2005, 108 (1-2) :758-764

[6] Direct detection of genomic DNA by enzymatically amplified SPR imaging measurements of RNA microarrays [J].

Goodrich, TT ;

Lee, HJ ;

Corn, RM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (13) :4086-4087

[7] OPTICAL-CONSTANTS OF WATER IN 200-NM TO 200-MUM WAVELENGTH REGION [J].

HALE, GM ;

QUERRY, MR .

APPLIED OPTICS, 1973, 12 (03) :555-563

[8] Dual-channel surface plasmon resonance sensor with spectral discrimination of sensing channels using dielectric overlayer [J].

Homola, J ;

Lu, HB ;

Yee, SS .

ELECTRONICS LETTERS, 1999, 35 (13) :1105-1106

[9] Surface plasmon resonance sensors: review [J].

Homola, J ;

Yee, SS ;

Gauglitz, G .

SENSORS AND ACTUATORS B-CHEMICAL, 1999, 54 (1-2) :3-15

[10] Surface plasmon resonance sensors based on diffraction gratings and prism couplers: sensitivity comparison [J].

Homola, J ;

Koudela, I ;

Yee, SS .

SENSORS AND ACTUATORS B-CHEMICAL, 1999, 54 (1-2) :16-24

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