DNA demethylation

被引：134

作者：

Wolffe, AP ^{[1
]}

Jones, PL ^{[1
]}

Wade, PA ^{[1
]}

机构：

[1] NICHHD, Mol Embryol Lab, NIH, Bethesda, MD 20892 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1999年 / 96卷 / 11期

关键词：

D O I：

10.1073/pnas.96.11.5894

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：5894 / 5896

页数：3

共 53 条

[1]

Baylin SB, 1998, ADV CANCER RES, V72, P141

[2] CLONING AND SEQUENCING OF A CDNA-ENCODING DNA METHYLTRANSFERASE OF MOUSE CELLS - THE CARBOXYL-TERMINAL DOMAIN OF THE MAMMALIAN ENZYMES IS RELATED TO BACTERIAL RESTRICTION METHYLTRANSFERASES [J].

BESTOR, T ;

LAUDANO, A ;

MATTALIANO, R ;

INGRAM, V .

JOURNAL OF MOLECULAR BIOLOGY, 1988, 203 (04) :971-983

[3] A mammalian protein with specific demethylase activity for mCpG DNA [J].

Bhattacharya, SK ;

Ramchandani, S ;

Cervoni, N ;

Szyf, M .

NATURE, 1999, 397 (6720) :579-583

[4] TRANSCRIPTIONAL NOISE AND THE EVOLUTION OF GENE NUMBER [J].

BIRD, A ;

TWEEDIE, S .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 1995, 349 (1329) :249-253

[5] CHROMATIN STRUCTURE IS REQUIRED TO BLOCK TRANSCRIPTION OF THE METHYLATED HERPES-SIMPLEX VIRUS THYMIDINE KINASE GENE [J].

BUSCHHAUSEN, G ;

WITTIG, B ;

GRAESSMANN, M ;

GRAESSMANN, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (05) :1177-1181

[6] Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer [J].

Cameron, EE ;

Bachman, KE ;

Myöhänen, S ;

Herman, JG ;

Baylin, SB .

NATURE GENETICS, 1999, 21 (01) :103-107

[7]

CEDAR H, 1999, NATURE, V397, P579

[8] DNA demethylase is a processive enzyme [J].

Cervoni, N ;

Bhattacharya, S ;

Szyf, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (13) :8363-8366

[9] DIRECT IDENTIFICATION OF THE ACTIVE-SITE NUCLEOPHILE IN A DNA (CYTOSINE-5)-METHYLTRANSFERASE [J].

CHEN, L ;

MACMILLAN, AM ;

CHANG, W ;

EZAZNIKPAY, K ;

LANE, WS ;

VERDINE, GL .

BIOCHEMISTRY, 1991, 30 (46) :11018-11025

[10] MUTATIONAL SEPARATION OF DNA-BINDING FROM CATALYSIS IN A DNA CYTOSINE METHYLTRANSFERASE [J].

CHEN, L ;

MACMILLAN, AM ;

VERDINE, GL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (12) :5318-5319

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