Elucidating the link between collagen and pancreatic cancer: what's next?

被引：14

作者：

Hamada, Shin ^{[1
]}

Masamune, Atsushi ^{[1
]}

机构：

[1] Tohoku Univ, Div Gastroenterol, Grad Sch Med, Sendai, Miyagi, Japan

来源：

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY | 2018年 / 12卷 / 04期

关键词：

Epithelial-mesenchymal transition; extracellular matrix; integrin; Kindlin; pancreatic stellate cells; DUCTAL ADENOCARCINOMA; STELLATE CELLS; GENE-EXPRESSION; MALIGNANT PHENOTYPE; DOWN-REGULATION; I COLLAGEN; E-CADHERIN; INTEGRIN; PROMOTES; PROGRESSION;

D O I：

10.1080/17474124.2018.1448268

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

引用

收藏

页码：315 / 317

页数：3

相关论文

共 33 条

[1]

Inhibition of Discoidin Domain Receptor 1 Reduces Collagen-mediated Tumorigenicity in Pancreatic Ductal Adenocarcinoma [J].

Aguilera, Kristina Y. ;

Huang, Huocong ;

Du, Wenting ;

Hagopian, Moriah M. ;

Wang, Zhen ;

Hinz, Stefan ;

Hwang, Tae Hyun ;

Wang, Huamin ;

Fleming, Jason B. ;

Castrillon, Diego H. ;

Ren, Xiaomei ;

Ding, Ke ;

Brekken, Rolf A. .

MOLECULAR CANCER THERAPEUTICS, 2017, 16 (11) :2473-2485

[2]

Desmoplastic reaction in pancreatic cancer - Role of pancreatic stellate cells [J].

Apte, MV ;

Park, S ;

Phillips, PA ;

Santucci, N ;

Goldstein, D ;

Kumar, RK ;

Ramm, GA ;

Buchler, M ;

Friess, H ;

McCarroll, JA ;

Keogh, G ;

Merrett, N ;

Pirola, R ;

Wilson, JS .

PANCREAS, 2004, 29 (03) :179-187

[3]

Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma [J].

Armstrong, T ;

Packham, G ;

Murphy, LB ;

Bateman, AC ;

Conti, JA ;

Fine, DR ;

Johnson, CD ;

Benyon, RC ;

Iredale, JP .

CLINICAL CANCER RESEARCH, 2004, 10 (21) :7427-7437

[4]

CONSEQUENCES OF LACK OF BETA-1 INTEGRIN GENE-EXPRESSION IN MICE [J].

FASSLER, R ;

MEYER, M .

GENES & DEVELOPMENT, 1995, 9 (15) :1896-1908

[5]

The α2β1 integrin mediates the malignant phenotype on type I collagen in pancreatic cancer cell lines [J].

Grzesiak, JJ ;

Bouvet, M .

BRITISH JOURNAL OF CANCER, 2006, 94 (09) :1311-1319

[6]

CHARACTERIZATION OF INTEGRIN CHAINS IN NORMAL AND NEOPLASTIC HUMAN PANCREAS [J].

HALL, PA ;

COATES, P ;

LEMOINE, NR ;

HORTON, MA .

JOURNAL OF PATHOLOGY, 1991, 165 (01) :33-41

[7]

Alteration of pancreatic cancer cell functions by tumor-stromal cell interaction [J].

Hamada, Shin ;

Masamune, Atsushi ;

Shimosegawa, Tooru .

FRONTIERS IN PHYSIOLOGY, 2013, 4

[8]

Collagen type I-induced Smad-interacting protein 1 expression downregulates E-cadherin in pancreatic cancer [J].

Imamichi, Y. ;

Koenig, A. ;

Gress, T. ;

Menke, A. .

ONCOGENE, 2007, 26 (16) :2381-2385

[9]

The good and the bad collagens of fibrosis - Their role in signaling and organ function [J].

Karsdal, M. A. ;

Nielsen, S. H. ;

Leeming, D. J. ;

Langholm, L. L. ;

Nielsen, M. J. ;

Manon-Jensen, T. ;

Siebuhr, A. ;

Gudmann, N. S. ;

Ronnow, S. ;

Sand, J. M. ;

Daniels, S. J. ;

Mortensen, J. H. ;

Schuppan, D. .

ADVANCED DRUG DELIVERY REVIEWS, 2017, 121 :43-56

[10]

Pancreatic stellate cells: A dynamic player of the intercellular communication in pancreatic cancer [J].

Masamune, Atsushi ;

Shimosegawa, Tooru .

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY, 2015, 39 :S98-S103

← 1 2 3 4 →