Coagulase-Negative Staphylococcal Infections

被引：299

作者：

Rogers, Kathie L. ^{[2
]}

Fey, Paul D. ^{[1
,2
]}

Rupp, Mark E. ^{[1
]}

机构：

[1] Univ Nebraska Med Ctr, Dept Internal Med, Omaha, NE 68198 USA

[2] Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Omaha, NE 68198 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2009年 / 23卷 / 01期

关键词：

Coagulase-negative Staphylococci; Staphylococcus epidermidis; Intravascular catheter-associated bloodstream infection; Biofilm; Prosthetic device infection; Staphylococcus haemolyticus; Staphylococcus saprophyticus; CENTRAL VENOUS CATHETERS; BLOOD-STREAM INFECTION; URINARY-TRACT INFECTION; NATIVE VALVE ENDOCARDITIS; IN-VIVO EFFICACY; SURGICAL SITE; INTERNATIONAL COLLABORATION; INTERCELLULAR-ADHESION; EPIDERMIDIS BIOFILMS; GEL-ELECTROPHORESIS;

D O I：

10.1016/j.idc.2008.10.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Coagulase-negative staphylococci (CNS) are differentiated from the closely related but more virulent Staphylococcus aureus by their inability to produce free coagulase. Currently, there are over 40 recognized species of CNS. These organisms typically reside on healthy human skin and mucus membranes, rarely cause disease, and are most frequently encountered by clinicians as contaminants of microbiological cultures. However, CNS have been increasingly recognized to cause clinically significant infections. The conversion of the CNS from symbiont to human pathogen has been a direct reflection of the use of indwelling medical devices. This article deals with the clinical syndromes, epidemiology, prevention, and management of infections caused by this unique group of organisms.

引用

页码：73 / +

页数：27

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