Identification of a DNA methyltransferase gene carried on a pathogenicity island-like element (VPAI) in Vibrio parahaemolyticus and its prevalence among clinical and environmental isolates

被引：26

作者：

Wang, Hui-zhen

Wong, Minnie M. L.

O'Toole, Desmond

Mak, Mandy M. H.

Wu, Rudolf S. S.

Kong, Richard Y. C.

机构：

[1] City Univ Hong Kong, Dept Biol & Chem, Kowloon, Hong Kong, Peoples R China

[2] City Univ Hong Kong, Res Ctr Coastal Pollut & Conservat, Kowloon, Hong Kong, Peoples R China

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2006年 / 72卷 / 06期

关键词：

D O I：

10.1128/AEM.02095-05

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In this study we identified a putative virulence-associated DNA methyltransferase (MTase) gene carried on a novel 22.79-kb pathogenicity island-like element (VPAI) in V. parahaemolyticus. The V. parahaemolyticus MTase gene was shown by PCR to be prevalent (> 98%) in pandemic thermostable direct hemolysin gene-positive isolates, which suggests that VPAI may confer unique virulence traits to pandemic strains of V. parahaemolyticus.

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页码：4455 / 4460

页数：6

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