Prevalence of coeliac disease in patients with thyroid autoimmunity

被引：73

作者：

Valentino, R

Savastano, S

Tommaselli, A

Dorato, M

Scarpitta, MT

Gigante, M

Micillo, M

Paparo, F

Petrone, E

Lombardi, G

Troncone, R

机构：

[1] Univ Naples Federico II, Chair Endocrinol, CNR,Expt Endocrinol & Oncol Ctr, Dept Cellular & Mol Biol & Pathol, I-80131 Naples, Italy

[2] Univ Naples Federico II, Dept Mol & Clin Endocrinol & Oncol, I-80131 Naples, Italy

[3] Univ Naples Federico II, Dept Pediat, I-80131 Naples, Italy

来源：

HORMONE RESEARCH | 1999年 / 51卷 / 03期

关键词：

autoimmune thyroid disease; coeliac disease; gliadin; endomysial antibodies;

D O I：

10.1159/000023344

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The occurrence of autoimmune thyroid disorders among patients with coeliac disease (CD) is well documented, but the exact prevalence of CD among patients with autoimmune thyroid diseases (ATD) is as yet unclear. We screened 150 newly diagnosed patients with ATD by serum endomysial antibody detection (EmA), In 5 subjects (3.3%) EmA positivity was found; all underwent jejunal biopsy. On gluten-free diet an excellent clinical and histological response was recorded with an improvement of hypothyroidism and reduction of the thyroxine dosage, Our data suggest a significant high prevalence (3.3%) of CD in patients with ATD, in particular with Hashimoto's thyroiditis.

引用

页码：124 / 127

页数：4

共 23 条

[1]

AURICCHIO S, 1990, GASTROENTEROLOGY INT, V3, P140

[2] CELIAC-DISEASE IN THE YEAR 2000 - EXPLORING THE ICEBERG [J].

CATASSI, C ;

RATSCH, IM ;

FABIANI, E ;

ROSSINI, M ;

BORDICCHIA, F ;

CANDELA, F ;

COPPA, GV ;

GIORGI, PL .

LANCET, 1994, 343 (8891) :200-203

[3] L-THYROXINE THERAPY INDUCES A FALL OF THYROID MICROSOMAL AND THYROGLOBULIN ANTIBODIES IN IDIOPATHIC MYXEDEMA AND IN HYPOTHYROID, BUT NOT IN EUTHYROID HASHIMOTOS-THYROIDITIS [J].

CHIOVATO, L ;

MARCOCCI, C ;

MARIOTTI, S ;

MORI, A ;

PINCHERA, A .

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1986, 9 (04) :299-305

[4] CELIAC-DISEASE - ASSOCIATED DISORDERS AND SURVIVAL [J].

COLLIN, P ;

REUNALA, T ;

PUKKALA, E ;

LAIPPALA, P ;

KEYRILAINEN, O ;

PASTERNACK, A .

GUT, 1994, 35 (09) :1215-1218

[5] AUTOIMMUNE THYROID-DISORDERS AND CELIAC-DISEASE [J].

COLLIN, P ;

SALMI, T ;

HALLSTROM, O ;

REUNALA, T ;

PASTERNACK, A .

EUROPEAN JOURNAL OF ENDOCRINOLOGY, 1994, 130 (02) :137-140

[6] CELIAC-DISEASE AND IMMUNOLOGICAL DISORDERS [J].

COOPER, BT ;

HOLMES, GKT ;

COOKE, WT .

BRITISH MEDICAL JOURNAL, 1978, 1 (6112) :537-539

[7] CELIAC-DISEASE AND AUTOIMMUNE THYROID-DISEASE [J].

COUNSELL, CE ;

TAHA, A ;

RUDDELL, WSJ .

GUT, 1994, 35 (06) :844-846

[8] THYROID ABNORMALITIES IN DERMATITIS-HERPETIFORMIS - PREVALENCE OF CLINICAL THYROID-DISEASE AND THYROID AUTOANTIBODIES [J].

CUNNINGHAM, MJ ;

ZONE, JJ .

ANNALS OF INTERNAL MEDICINE, 1985, 102 (02) :194-196

[9]

GORDIN A, 1975, LANCET, V2, P1234

[10] MALIGNANCY IN CELIAC-DISEASE - EFFECT OF A GLUTEN FREE DIET [J].

HOLMES, GKT ;

PRIOR, P ;

LANE, MR ;

POPE, D ;

ALLAN, RN .

GUT, 1989, 30 (03) :333-338

← 1 2 3 →