Enzymes - Picking a winner

被引：25

作者：

Sheldon, R ^{[1
]}

机构：

[1] Delft Univ Technol, Dept Organ Chem & Catalysis, NL-2628 BL Delft, Netherlands

来源：

NATURE | 1999年 / 399卷 / 6737期

关键词：

D O I：

10.1038/21316

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The industrial application of certain enzymes such as cytochrome P450 monooxygenases has been limited by the need for cofactors. An improved way of bypassing the cofactor system has been discovered by ‘directed evolution’, a process which mimics enzyme evolution in the laboratory.

引用

页码：636 / 637

页数：2