Immunization therapy in Alzheimer's disease

被引:3
作者
Mor, Felix [1 ,2 ]
Monsonego, Alon [3 ,4 ]
机构
[1] Tel Aviv Univ, Weizmann Inst Sci, Dept Immunol, Rehovot, Israel
[2] Sackler Fac Med, Rabin Med Ctr, Dept Med B, Tel Aviv, Israel
[3] Ben Gurion Univ Negev, Natl Inst Biotechnol, IL-84105 Beer Sheva, Israel
[4] Ben Gurion Univ Negev, Dept Microbiol & Immunol, Fac Hlth Sci, IL-84105 Beer Sheva, Israel
关键词
Alzheimer's disease; clinical trials; meningoencephalitis; Th1/Th2; balance; vaccination;
D O I
10.1586/14737175.6.5.653
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Alzheimer's disease (AD) is a common and devastating neurodegenerative disease. The incidence of AD is increasing in Western societies. The current treatment of AD is mostly symptomatic and ineffective in stopping or reversing the cognitive impairment. One of the exciting and effective new treatments developed in experimental AD is immunization against amyloid-beta peptide. This article provides an overview of immunization therapy in AD and examines the future prospects of this therapeutic modality.
引用
收藏
页码:653 / 659
页数:7
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