Structure and function of the P-type ATPases

被引：38

作者：

Scarborough, GA ^{[1
]}

机构：

[1] Univ N Carolina, Dept Pharmacol, Chapel Hill, NC 27599 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 04期

关键词：

D O I：

10.1016/S0955-0674(99)80075-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The P-type ATPases are integral membrane proteins that generate essential transmembrane ion gradients in virtually all living cells. The structures of two of these have recently been elucidated at a resolution of 8 Angstrom. When considered together with the large body of biochemical information that has accrued for these transporters and for enzymes in general, this new structural information is providing tantalizing insights regarding the molecular mechanism of active ion transport catalyzed by these proteins.

引用

页码：517 / 522

页数：6

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