Treatment of Gastroparesis: An Update

被引:18
作者
Gumaste, Vivek
Baum, Joel
机构
[1] Elmhurst Gen Hosp, Dept Med, Mt Sinai Serv, Elmhurst, NY USA
[2] CUNY, Mt Sinai Sch Med, New York, NY 10021 USA
关键词
Gastroparesis; Diabetes;
D O I
10.1159/000185690
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Gastroparesis is a chronic disorder of gastric motility that is characterized by delayed emptying of either solids or liquids from the stomach in the absence of any mechanical obstruction. Nausea, vomiting, early satiety and bloating are some of the manifestations of gastroparesis. Idiopathic, diabetes mellitus and postsurgical states account for the majority of cases. Gastroparesis is a difficult condition to treat. Prokinetic drugs like metoclopramide and erythromycin form the mainstay of therapy but are less than ideal. Some patients may benefit from endoscopic botolinium toxin injection. Gastric electrical stimulation, though promising, is not ready for prime time yet. Copyright (C) 2008 S. Karger AG, Basel
引用
收藏
页码:173 / 179
页数:7
相关论文
共 51 条
[1]
Gastric electrical stimulation for medically refractory gastroparesis [J].
Abell, T ;
McCallum, R ;
Hocking, M ;
Koch, K ;
Abrahamsson, H ;
LeBlanc, I ;
Lindberg, G ;
Konturek, J ;
Nowak, T ;
Quigley, EMM ;
Tougas, G ;
Starkebaum, W .
GASTROENTEROLOGY, 2003, 125 (02) :421-428
[2]
Treatment of gastroparesis: a multidisciplinary clinical review [J].
Abell, TL ;
Bernstein, RK ;
Cutts, T ;
Farrugia, G ;
Forster, J ;
Hasler, WL ;
McCallum, RW ;
Olden, KW ;
Parkman, HP ;
Parrish, CR ;
Pasricha, PJ ;
Prather, CM ;
Soffer, EE ;
Twillman, R ;
Vinik, AI .
NEUROGASTROENTEROLOGY AND MOTILITY, 2006, 18 (04) :263-283
[3]
Gastric electrical stimulation in intractable symptomatic gastroparesis [J].
Abell, TL ;
Van Cutsem, E ;
Abrahamsson, H ;
Huizinga, JD ;
Konturek, JW ;
Galmiche, JP ;
Voeller, G ;
Filez, L ;
Everts, B ;
Waterfall, WE ;
Domschke, W ;
des Varannes, SB ;
Familoni, BO ;
Bourgeois, IM ;
Janssens, J ;
Tougas, G .
DIGESTION, 2002, 66 (04) :204-212
[4]
Gastric electrical stimulation is safe and effective: A long-term study in patients with drug-refractory gastroparesis in three regional centers [J].
Anand, Curuchi ;
Al-Juburi, Amar ;
Familoni, Babajide ;
Rashed, Hani ;
Cutts, Teresa ;
Abidi, Nighat ;
Johnson, William D. ;
Minocha, Anil ;
Abell, Thomas L. .
DIGESTION, 2007, 75 (2-3) :83-89
[5]
Gastric electrical stimulation for the treatment of gastroparesis: Ready for prime time? [J].
Ang, D. ;
Tack, J. .
DIGESTION, 2007, 75 (2-3) :80-82
[6]
Clinical trial: a randomized-controlled crossover study of intrapyloric injection of botulinum toxin in gastroparesis [J].
Arts, J. ;
Holvoet, L. ;
Caenepeel, P. ;
Bisschops, R. ;
Sifrim, D. ;
Verbeke, K. ;
Janssens, J. ;
Tack, J. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2007, 26 (09) :1251-1258
[7]
Influence of intrapyloric botulinum toxin injection on gastric emptying and meal-related symptoms in gastroparesis patients [J].
Arts, J. . ;
Van Gool, S. ;
Caenepeel, P. ;
Verbeke, K. ;
Janssens, J. ;
Tack, J. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2006, 24 (04) :661-667
[8]
Temporary gastric-electrical stimulation with orally or PEG-placed electrodes in patients with drug refractory gastroparesis [J].
Ayinala, S ;
Batista, O ;
Goyal, A ;
Al-Juburi, A ;
Abidi, N ;
Familoni, B ;
Abell, T .
GASTROINTESTINAL ENDOSCOPY, 2005, 61 (03) :455-461
[9]
Endoscopic pyloric injection of botulinum toxin A for the treatment of refractory gastroparesis [J].
Bromer, MQ ;
Friedenberg, F ;
Miller, LS ;
Fisher, RS ;
Swartz, K ;
Parkman, HR .
GASTROINTESTINAL ENDOSCOPY, 2005, 61 (07) :833-839
[10]
CAMILLERI M, 1993, AM J GASTROENTEROL, V88, P169