Inflammatory breast cancer

被引:24
作者
Cariati, M [1 ]
Bennett-Britton, TM [1 ]
Pinder, SE [1 ]
Purushotham, AD [1 ]
机构
[1] Univ Cambridge Hosp, NHS Fdn Trust, Cambridge Breast Unit, Addenbrookes Hosp, Cambridge CB2 2QQ, England
来源
SURGICAL ONCOLOGY-OXFORD | 2005年 / 14卷 / 03期
关键词
inflammatory breast cancer; multiniodality treatment;
D O I
10.1016/j.suronc.2005.07.004
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Background: "Inflammatory" breast cancer is a rare and very aggressive form of the disease characterised by rapid onset and dismal outcome. Methods: This review describes the clinical and molecular aspects of inflammatory breast cancer. The relevant English language literature on of inflammatory breast cancer was searched via Medline and ISI Web of Knowledge(SM) Cross Search (1924-2005), cross-referencing with key articles on the subject. Results and conclusion: An increasing body of evidence demonstrates that inflammatory breast cancer is a unique form of breast cancer. A prompt diagnosis and multidisciplinary approach (based on neoadjuvant chemotherapy, loco-regional treatment with surgery and/or radiotherapy, followed in some cases by adjuvant systemic therapy) are the two factors most likely to have an impact on survival. As the molecular basis of the disease is becoming increasingly more defined, new potential therapeutic targets may arise in the future. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:133 / 143
页数:11
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