Aspirin in the prevention of strokes

被引：9

作者：

Diener, HC ^{[1
]}

机构：

[1] Univ Essen Gesamthsch, Dept Neurol, D-45122 Essen, Germany

来源：

BIOMEDICINE & PHARMACOTHERAPY | 1999年 / 53卷 / 07期

关键词：

aspirin; hemorrhage; secondary prevention; stroke;

D O I：

10.1016/S0753-3322(00)88501-7

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Aspirin leads to a moderate but significant reduction of stroke, myocardial infarction (MI), and vascular deaths in patients with transient ischemic attack (TIA) and ischemic stroke. Low doses are as effective as high doses but are better tolerated in terms of gastrointestinal side-effects. The recommended daily aspirin dose is therefore between 50 and 325 mg. Bleeding complications are not dose dependent and occur with the lowest doses. (C) 1999 Elsevier, Paris.

引用

页码：309 / 311

页数：3

共 31 条

[1] Aspirin at any dose above 30 mg offers only modest protection after cerebral ischaemia [J].

Algra, A ;

vanGijn, J .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1996, 60 (02) :197-199

[2] Cumulative meta-analysis of aspirin efficacy after cerebral ischaemia of arterial origin [J].

Algra, A ;

Van Gijn, J .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1999, 66 (02) :255-255

[3] COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS [J].

ALTMAN, R ;

CARRERAS, L ;

DIAZ, R ;

FIGUEROA, E ;

PAOLASSO, E ;

PARODI, JC ;

CADE, JF ;

DONNAN, G ;

EADIE, MJ ;

GAVAGHAN, TP ;

OSULLIVAN, EF ;

PARKIN, D ;

RENNY, JTG ;

SILAGY, C ;

VINAZZER, H ;

ZEKERT, F ;

ADRIAENSEN, H ;

BERTRANDHARDY, JM ;

BRAN, M ;

DAVID, JL ;

DRICOT, J ;

LAVENNEPARDONGE, E ;

LIMET, R ;

LOWENTHAL, A ;

MORIAU, M ;

SCHAPIRA, S ;

SMETS, P ;

SYMOENS, J ;

VERHAEGHE, R ;

VERSTRAETE, M ;

ATALLAH, A ;

BARNETT, H ;

BATISTA, R ;

BLAKELY, J ;

CAIRNS, JA ;

COTE, R ;

CROUCH, J ;

EVANS, G ;

FINDLAY, JM ;

GENT, M ;

LANGLOIS, Y ;

LECLERC, J ;

NORRIS, J ;

PINEO, GF ;

POWERS, PJ ;

ROBERTS, R ;

SCHWARTZ, L ;

SICURELLA, J ;

TAYLOR, W ;

THEROUX, P .

BMJ-BRITISH MEDICAL JOURNAL, 1994, 308 (6921) :81-100

[4]

[Anonymous], 1988, BRIT MED J, V296, P320

[5]

[Anonymous], 1991, Lancet, V338, P1345

[6]

[Anonymous], 1978, N ENGL J MED

[7] Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis [J].

Barnett, HJM ;

Taylor, W ;

Eliasziw, M ;

Fox, AJ ;

Ferguson, GG ;

Haynes, RB ;

Rankin, RN ;

Clagett, GP ;

Hachinski, VC ;

Sackett, DL ;

Thorpe, KE ;

Meldrum, HE ;

Spence, JD .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (20) :1415-1425

[8] AICLA CONTROLLED TRIAL OF ASPIRIN AND DIPYRIDAMOLE IN THE SECONDARY PREVENTION OF ATHERO-THROMBOTIC CEREBRAL-ISCHEMIA [J].

BOUSSER, MG ;

ESCHWEGE, E ;

HAGUENAU, M ;

LEFAUCCONNIER, JM ;

THIBULT, N ;

TOUBOUL, D ;

TOUBOUL, PJ .

STROKE, 1983, 14 (01) :5-14

[9] Aspirin or heparin immediately after a stroke? [J].

Bousser, MG .

LANCET, 1997, 349 (9065) :1564-1565

[10] CAST: Randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke [J].

Chen, ZM ;

Hui, JM ;

Liu, LS ;

Liu, ZM ;

Peto, R ;

Sandercock, P ;

Wang, WQ ;

Wang, YX ;

Wang, ZB ;

Xie, JX ;

You, GX ;

Zhang, FL ;

Zhang, HQ ;

Zhao, ZY .

LANCET, 1997, 349 (9066) :1641-1649

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