First description of Klebsiella pneumoniae harboring CTX-M β-lactamases (CTX-M-14 and CTX-M-3) in Taiwan

被引：46

作者：

Yu, WL

Winokur, PL

Von Stein, DL

Pfaller, MA

Wang, JH

Jones, RN ^{[1
]}

机构：

[1] JMI Labs, JONES Grp, 345 Beaver Kreek Ctr,Suite A, North Liberty, IA 52317 USA

[2] Univ Iowa, Coll Med, Iowa City, IA USA

[3] Vet Affairs Med Ctr, Iowa City, IA 52242 USA

[4] China Med Coll Hosp, Taichung, Taiwan

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 04期

关键词：

D O I：

10.1128/AAC.46.4.1098-1100.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Klebsiella pneumoniae isolates from Taiwan medical centers (50 strains; 1998 to 2000) with a CTX-M resistance phenotype (ceftazidime susceptible and ceftriaxone or cefotaxime nonsusceptible) were selected for initial isoelectric focusing analysis. beta-Lactamases with pIs of 7.9 (n = 22) and 8.4 (n = 28) in addition to 5.4 and/or 7.6 were detected. DNA gene sequencing identified the beta-lactamases with pIs of 7.9 and 8.4 as CTX-M-14 and CTX-M-3, respectively. Molecular typing suggested inter- and intrahospital clonal dissemination of these Taiwanese CTX-M-producing Klebsiella strains.

引用

页码：1098 / 1100

页数：3

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