Endocrine disrupting nonylphenols are ubiquitous in food

被引:352
作者
Guenther, K [1 ]
Heinke, V [1 ]
Thiele, B [1 ]
Kleist, E [1 ]
Prast, H [1 ]
Raecker, T [1 ]
机构
[1] Forschungszentrum Julich, Inst Appl Phys Chem, Res Ctr, D-52425 Julich, Germany
关键词
D O I
10.1021/es010199v
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
4-Nonylphenols (NPs) are common products of biodegradation of a widely used group of nonionic surfactants, the nonylphenol ethoxylates (NPEs). These compounds are known to be persistent, toxic, and estrogen active. There is a worldwide scientific and public discussion on the potential consequences of human long term dietary exposure to such endocrine disrupters. Despite numerous determinations of NIPS in environmental samples no systematical reports exist relating to concentrations of NPs in food. We analyzed NPs in 60 different foodstuff commercially available in Germany. The results indicate that NPs are ubiquitous in food. The concentrations of NPs on a fresh weight basis varied between 0.1 and 19.4 mug/kg regardless of the fat content of the foodstuff. Based on data on German food consumption rates and these first analyses of NPs in food, the daily intake for an adult was calculated to be 7.5 mug/day NPs. For infants exclusively fed with breast milk or infant formulas daily intakes of 0.2 mug/day and 1.4 mug/day NPs, respectively, can be estimated.
引用
收藏
页码:1676 / 1680
页数:5
相关论文
共 35 条
[1]   BIOACCUMULATION OF THE LIPOPHILIC METABOLITES OF NONIONIC SURFACTANTS IN FRESH-WATER ORGANISMS [J].
AHEL, M ;
MCEVOY, J ;
GIGER, W .
ENVIRONMENTAL POLLUTION, 1993, 79 (03) :243-248
[2]   DETERMINATION OF ALKYLPHENOLS AND ALKYLPHENOL MONOETHOXYLATE AND DIETHOXYLATE IN ENVIRONMENTAL-SAMPLES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].
AHEL, M ;
GIGER, W .
ANALYTICAL CHEMISTRY, 1985, 57 (08) :1577-1583
[3]   BEHAVIOR OF ALKYLPHENOL POLYETHOXYLATE SURFACTANTS IN THE AQUATIC ENVIRONMENT .1. OCCURRENCE AND TRANSFORMATION IN SEWAGE-TREATMENT [J].
AHEL, M ;
GIGER, W ;
KOCH, M .
WATER RESEARCH, 1994, 28 (05) :1131-1142
[4]   Exposure to exogenous estrogens in food: possible impact on human development and health [J].
Andersson, AM ;
Skakkebaek, NE .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 1999, 140 (06) :477-485
[5]   SEPARATION AND CHARACTERIZATION OF ISOMERS OF PARA-NONYLPHENOLS BY CAPILLARY GC/GC-MS/GC-FTIR TECHNIQUES [J].
BHATT, BD ;
PRASAD, JV ;
KALPANA, G ;
ALI, S .
JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1992, 30 (06) :203-210
[6]   4-NONYLPHENOL IN SEWAGE-SLUDGE - ACCUMULATION OF TOXIC METABOLITES FROM NONIONIC SURFACTANTS [J].
GIGER, W ;
BRUNNER, PH ;
SCHAFFNER, C .
SCIENCE, 1984, 225 (4662) :623-625
[7]   PERSISTENT ORGANIC-CHEMICALS IN SEWAGE EFFLUENTS .1. IDENTIFICATIONS OF NONYLPHENOLS AND NONYLPHENOLETHOXYLATES BY GLASS-CAPILLARY GAS CHROMATOGRAPHY-MASS SPECTROMETRY [J].
GIGER, W ;
STEPHANOU, E ;
SCHAFFNER, C .
CHEMOSPHERE, 1981, 10 (11-1) :1253-1263
[8]   COMPOSITIONAL ANALYSIS OF COMMERCIAL PVC BOTTLES AND STUDIES OF ASPECTS OF SPECIFIC AND OVERALL MIGRATION INTO FOODS AND SIMULANTS [J].
GILBERT, J ;
STARTIN, JR ;
MCGUINNESS, JD .
FOOD ADDITIVES AND CONTAMINANTS, 1986, 3 (02) :133-143
[9]   Induction of testis-ova in Japanese medaka (Oryzias latipes) exposed to p-nonylphenol [J].
Gray, MA ;
Metcalfe, CD .
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 1997, 16 (05) :1082-1086
[10]  
HAGER CD, 1998, ANN SURFACTANT REV, P1