DNA cleavage activities of (-)-epigallocatechin, (-)-epicatechin, (+)-catechin, and (-)-epigallocatechin gallate with various kind of metal ions

被引：39

作者：

Hayakawa, F

Kimura, T ^{[1
]}

Hoshino, N

Ando, T

机构：

[1] Shiga Univ Med Sci, Dept Chem, Shiga 5202192, Japan

[2] Shiga Univ Med Sci, Dept Pharm, Shiga 5202192, Japan

[3] Univ Shiga Prefecture, Sch Human Cultures, Dept Life Style Studies, Shiga 5228533, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1999年 / 63卷 / 09期

关键词：

catechin; metal ion; DNA cleavage; antioxidant; prooxidant;

D O I：

10.1271/bbb.63.1654

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The DNA cleavage activities of (+)-catechin (C), (-)epicatechin (EC), (-)-epigallocatechin (EGC), and (-)-epigallocatechin gallate (EGCg) were examined with 16 different metal ions. Cu2+ with all the catechins facilitated DNA cleavage, while Ag+ with EGC and EC showed a strong repressive effect. The other metal ions examined showed little effect.

引用

页码：1654 / 1656

页数：3

共 8 条

[1] DNA cleavage reaction and linoleic acid peroxidation induced by tea catechins in the presence of cupric ion [J].