High average daily intake of PCDD/Fs and serum levels in residents living near a deserted factory producing pentachlorophenol (PCP) in Taiwan: Influence of contaminated fish consumption

被引:31
作者
Lee, CC
Lin, WT
Liao, PC
Su, HJ
Chen, HL
机构
[1] Hung Kuang Univ, Dept Ind Safety & Hlth, Taichung 433, Taiwan
[2] Natl Cheng Kung Univ, Dept Environm & Occupat Hlth, Coll Med, Tainan 70101, Taiwan
[3] Natl Cheng Kung Univ, Res Ctr Environm Trace Tox Subst, Coll Med, Tainan 70101, Taiwan
关键词
PCDD/Fs; pentachlorophenol; fish; shrimp; oyster; ADI;
D O I
10.1016/j.envpol.2005.08.032
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
An abandoned pentachlorophenol plant and nearby area in southern Taiwan was heavily contaminated by dioxins, impurities formed in the PCP production process. The investigation showed that the average serum PCDD/Fs of residents living nearby area (62.5 pg WHO-TEQ/g lipid) was higher than those living in the non-polluted area (22.5 and 18.2 pg WHO-TEQ/g lipid) (P < 0.05). In biota samples, average PCDD/F of milkfish in sea reservoir (28.3 pg WHO-TEQ/g) was higher than those in the nearby fish farm (0.15 pg WHO-TEQ/g), and Tilapia and shrimp showed the similar trend. The average daily PCDD/Fs intake of 38% participants was higher than 4 pg WHO-TEQ/kg/day suggested by the world health organization. Serum PCDD/F was positively associated with average daily intake (ADI) after adjustment for age, sex, BMI, and smoking status. In addition, a prospective cohort study is suggested to determine the long-term health effects on the people living near factory. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:381 / 386
页数:6
相关论文
共 31 条
[1]   THE ESTIMATION OF TOTAL SERUM-LIPIDS BY A COMPLETELY ENZYMATIC SUMMATION METHOD [J].
AKINS, JR ;
WALDREP, K ;
BERNERT, JT .
CLINICA CHIMICA ACTA, 1989, 184 (03) :219-226
[2]   PCBs and dioxin-like compounds in plasma of adult Inuit living in Nunavik (Arctic Quebec) [J].
Ayotte, P ;
Dewailly, E ;
Ryan, JJ ;
Bruneau, S ;
Lebel, G .
CHEMOSPHERE, 1997, 34 (5-7) :1459-1468
[3]   Dioxins and furans: Epidemiologic assessment of cancer risks and other human health effects - Introduction [J].
Becher, H ;
Flesch-Janys, D .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1998, 106 :623-624
[4]   Blood levels of polychlorinated dibenzodioxins, polychlorinated dibenzofurans and polychlorinated biphenyls in the general population of a Spanish Mediterranean city. [J].
Ca, CG ;
Kogevinas, M ;
Huici, A ;
Gadea, E ;
Ladona, M ;
Bosch, A ;
Bleda, M .
CHEMOSPHERE, 1998, 36 (03) :419-426
[5]   SAMPLE CLEANUP BY SOLID-PHASE EXTRACTION FOR THE ULTRATRACE DETERMINATION OF POLYCHLORINATED DIBENZO-P-DIOXINS AND DIBENZOFURANS IN BIOLOGICAL SAMPLES [J].
CHANG, RR ;
JARMAN, WM ;
HENNINGS, JA .
ANALYTICAL CHEMISTRY, 1993, 65 (18) :2420-2427
[6]   Associations between dietary intake and serum polychlorinated dibenzo-p-dioxin and dibenzofuran (PCDD/F) levels in Taiwanese [J].
Chen, HL ;
Lee, CC ;
Liao, PC ;
Guo, YL ;
Chen, CH ;
Su, HJ .
ENVIRONMENTAL RESEARCH, 2003, 91 (03) :172-178
[7]   Serum PCDD/F concentration distribution in residents living in the vicinity of an incinerator and its association with predicted ambient dioxin exposure [J].
Chen, HL ;
Su, HJ ;
Liao, PC ;
Chen, CH ;
Lee, CC .
CHEMOSPHERE, 2004, 54 (10) :1421-1429
[8]   Chlorinated dibenzodioxins and dibenzofurans (PCDD/F) in blood and human milk of non occupationally exposed persons living in the vicinity of a municipal waste incinerator [J].
Deml, E ;
Mangelsdorf, I ;
Greim, H .
CHEMOSPHERE, 1996, 33 (10) :1941-1950
[9]   PCDDs and PCDFs in food samples from Catalonia, Spain. An assessment of dietary intake [J].
Domingo, JL ;
Schuhmacher, M ;
Granero, S ;
Llobet, JM .
CHEMOSPHERE, 1999, 38 (15) :3517-3528
[10]   Secondary exposure to dioxins through exposure to PCP and its derivatives [J].
Eduljee, G .
SCIENCE OF THE TOTAL ENVIRONMENT, 1999, 232 (03) :193-214