Human Tyk2 kinase deficiency: Another primary immunodeficiency syndrome

被引：46

作者：

Watford, Wendy T. ^{[1
]}

O'Shea, John J. ^{[1
]}

机构：

[1] NIAMSD, Mol Immunol & Inflammat Branch, NIH, Bethesda, MD 20892 USA

来源：

IMMUNITY | 2006年 / 25卷 / 05期

关键词：

D O I：

10.1016/j.immuni.2006.10.007

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：695 / 697

页数：3

共 10 条

[1] Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor
Changelian, PS
Flanagan, ME
Ball, DJ
Kent, CR
Magnuson, KS
Martin, WH
Rizzuti, BJ
Sawyer, PS
Perry, BD
Brissette, WH
McCurdy, SP
Kudlacz, EM
Conklyn, MJ
Elliott, EA
Koslov, ER
Fisher, MB
Strelevitz, TJ
Yoon, K
Whipple, DA
Sun, JM
Munchhof, MJ
Doty, JL
Casavant, JM
Blumenkopf, TA
Hines, M
Brown, MF
Lillie, BM
Subramanyam, C
Shang-Poa, C
Milici, AJ
Beckius, GE
Moyer, JD
Su, CY
Woodworth, TG
Gaweco, AS
Beals, CR
Littman, BH
Fisher, DA
Smith, JF
Zagouras, P
Magna, HA
Saltarelli, MJ
Johnson, KS
Nelms, LF
Des Etages, SG
Hayes, LS
Kawabata, TT
Finco-Kent, D
Baker, DL
Larson, M
[J]. SCIENCE, 2003, 302 (5646) : 875 - 878
[2] JAK-STAT PATHWAYS AND TRANSCRIPTIONAL ACTIVATION IN RESPONSE TO IFNS AND OTHER EXTRACELLULAR SIGNALING PROTEINS
DARNELL, JE
KERR, IM
STARK, GR
[J]. SCIENCE, 1994, 264 (5164) : 1415 - 1421
[3] Partial impairment of cytokine responses in Tyk2-deficient mice
Karaghiosoff, M
Neubauer, H
Lassnig, C
Kovarik, P
Schindler, H
Pircher, H
McCoy, B
Bogdan, C
Decker, T
Brem, G
Pfeffer, K
Müller, M
[J]. IMMUNITY, 2000, 13 (04) : 549 - 560
[4] MUTATIONS OF JAK-3 GENE IN PATIENTS WITH AUTOSOMAL SEVERE COMBINED IMMUNE-DEFICIENCY (SCID)
MACCHI, P
VILLA, A
GILIANI, S
SACCO, MG
FRATTINI, A
PORTA, F
UGAZIO, AG
JOHNSTON, JA
CANDOTTI, F
O'SHEA, JJ
VEZZONI, P
NOTARANGELO, LD
[J]. NATURE, 1995, 377 (6544) : 65 - 68
[5] Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
Minegishi, Yoshiyuki
Saito, Masako
Morio, Tomohiro
Watanabe, Ken
Agematsu, Kazunaga
Tsuchiya, Shigeru
Takada, Hidetoshi
Hara, Toshiro
Kawamura, Nobuaki
Ariga, Tadashi
Kaneko, Hideo
Kondo, Naomi
Tsuge, Ikuya
Yachie, Akihiro
Sakiyama, Yukio
Iwata, Tsutomu
Bessho, Fumio
Ohishi, Tsutomu
Joh, Kosuke
Imai, Kohsuke
Kogawa, Kazuhiro
Shinohara, Miwa
Fujieda, Mikiya
Wakiguchi, Hiroshi
Pasic, Srdjan
Abinun, Mario
Ochs, Hans D.
Renner, Eleonore D.
Jansson, Annette
Belohradsky, Bernd H.
Ayse, Metin
Shimizu, Norio
Mizutani, Shuki
Miyawaki, Toshio
Nonoyama, Shigeaki
Karasuyama, Hajime
[J]. IMMUNITY, 2006, 25 (05) : 745 - 755
[6] Mycobacterial diseases in primary immunodeficiencies
Reichenbach, Janine
Rosenzweig, Sergio
Doeffinger, Rainer
Dupuis, Stephanie
Holland, Steven M.
Casanova, Jean-Laurent
[J]. CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 1 (06) : 503 - 511
[7] A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity
Shaw, MH
Boyartchuk, V
Wong, S
Karaghiosoff, M
Ragimbeau, J
Pellegrini, S
Muller, M
Dietrich, WF
Yap, GS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (20) : 11594 - 11599
[8] Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-γ-dependent IL-10 reactivation
Shaw, Michael H.
Freeman, Gordon J.
Scott, Mark F.
Fox, Barbara A.
Bzik, David J.
Belkaid, Yasmine
Yap, George S.
[J]. JOURNAL OF IMMUNOLOGY, 2006, 176 (12) : 7263 - 7271
[9] Tyk2 plays a restricted role in IFNα signaling, although it is required for IL-12-mediated T cell function
Shimoda, K
Kato, K
Aoki, K
Matsuda, T
Miyamoto, A
Shibamori, M
Yamashita, M
Numata, A
Takase, K
Kobayashi, S
Shibata, S
Asano, Y
Gondo, H
Sekiguchi, K
Nakayama, K
Nakayama, T
Okamura, T
Okamura, S
Niho, Y
Nakayama, K
[J]. IMMUNITY, 2000, 13 (04) : 561 - 571
[10] A PROTEIN TYROSINE KINASE IN THE INTERFERON-ALPHA/BETA SIGNALING PATHWAY
VELAZQUEZ, L
FELLOUS, M
STARK, GR
PELLEGRINI, S
[J]. CELL, 1992, 70 (02) : 313 - 322

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