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Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis
被引：81
作者：
Cailliez, M.
Garaix, F.
Rousset-Rouviere, C.
Bruno, D.
Kone-Paut, I.
Sarles, J.
Chabrol, B.
Tsimaratos, M.
[1
]
机构：
[1] AP HM Timone Enfants, F-13385 Marseille 05, France
[2] Hop Bicetre, Dept Pediat, Paris, France
关键词：
D O I：
10.1007/s10545-006-0408-7
中图分类号：
R5 [内科学];
学科分类号：
1002 ;
100201 ;
摘要：
Hyper-IgD and periodic fever syndrome (HIDS) is a hereditary autoinflammatory syndrome, characterized by recurrent inflammatory attacks. Treatment of HIDS is difficult. Recently, the IL-1ra analogue anakinra was reported to be successful in aborting the IgD inflammatory attacks in a vaccination model. We report a clinical case of spectacular reduction of febrile attacks in a severe HIDS patient.
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页码：763 / 763
页数：1
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