BRCA1: an emerging role in the cellular response to DNA damage

[1] Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome [J]. SCIENCE, 1999, 286 (5449) : 2528 - 2531

[2] Chehab NH, 2000, GENE DEV, V14, P278

[3] Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells [J]. MOLECULAR CELL, 1998, 2 (03) : 317 - 328

[4] Requirement of ATM-dependent phosphorylation of BRCA1 in the DNA damage response to double-strand breaks [J]. SCIENCE, 1999, 286 (5442) : 1162 - 1166

[5] The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse [J]. CELL, 1996, 85 (07) : 1009 - 1023

[6] Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1 [J]. CELL, 1999, 97 (05) : 575 - 586

[7] DNA damage-induced activation of p53 by the checkpoint kinase Chk2 [J]. SCIENCE, 2000, 287 (5459) : 1824 - 1827

[8] hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response [J]. NATURE, 2000, 404 (6774) : 201 - 204

[9] GERM LINE P53 MUTATIONS IN A FAMILIAL SYNDROME OF BREAST-CANCER, SARCOMAS, AND OTHER NEOPLASMS [J]. SCIENCE, 1990, 250 (4985) : 1233 - 1238

[10] Linkage of ATM to cell cycle regulation by the Chk2 protein kinase [J]. SCIENCE, 1998, 282 (5395) : 1893 - 1897

[1] Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome [J]. SCIENCE, 1999, 286 (5449) : 2528 - 2531

[2] Chehab NH, 2000, GENE DEV, V14, P278

[3] Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells [J]. MOLECULAR CELL, 1998, 2 (03) : 317 - 328

[4] Requirement of ATM-dependent phosphorylation of BRCA1 in the DNA damage response to double-strand breaks [J]. SCIENCE, 1999, 286 (5442) : 1162 - 1166

[5] The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse [J]. CELL, 1996, 85 (07) : 1009 - 1023

[6] Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1 [J]. CELL, 1999, 97 (05) : 575 - 586

[7] DNA damage-induced activation of p53 by the checkpoint kinase Chk2 [J]. SCIENCE, 2000, 287 (5459) : 1824 - 1827

[8] hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response [J]. NATURE, 2000, 404 (6774) : 201 - 204

[9] GERM LINE P53 MUTATIONS IN A FAMILIAL SYNDROME OF BREAST-CANCER, SARCOMAS, AND OTHER NEOPLASMS [J]. SCIENCE, 1990, 250 (4985) : 1233 - 1238

[10] Linkage of ATM to cell cycle regulation by the Chk2 protein kinase [J]. SCIENCE, 1998, 282 (5395) : 1893 - 1897