Reproducibility of twitch and sniff transdiaphragmatic pressures

被引:30
作者
Luo, YM
Hart, N
Mustfa, N
Man, WDC
Rafferty, GF
Polkey, MI
Moxham, J
机构
[1] Kings Coll Hosp London, Guys Kings & St Thomas Sch Med, Resp Muscle Lab, Dept Resp Med & Allergy, London SE5 9PJ, England
[2] Royal Brompton Hosp, Resp Muscle Lab, London SW3 6LY, England
关键词
mammals; humans; methods; magnetic stimulation; diaphragm; muscle; nerve; phrenic; pressure; twitch; transdiaphragmatic;
D O I
10.1016/S1569-9048(02)00115-5
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Twitch transdiaphragmatic pressure (Tw Pdi) measured with magnetic stimulation of the phrenic nerve is used to follow up patients and to assess the effect of clinical treatments on diaphragm function. However the reproducibility of Tw Pdi on different occasions has been little studied. We investigated 32 normal subjects, measuring Tw Pdi elicited by bilateral magnetic stimulation of the phrenic nerves on two to 14 occasions. Sniff transdiaphragmatic pressure (sniff Pdi) was also measured. The mean value of Tw Pdi and sniff Pdi were 28 +/- 5 and 134 +/- 24 cm H2O, respectively. The within subjects coefficient of variation was 11% for both Tw Pdi and sniff Pdi. We conclude that there is a variability of Tw Pdi and the variability of Tw Pdi is the same as that of sniff Pdi. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:301 / 306
页数:6
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