Remote, 1,5-anti stereoinduction in the boron-mediated aldol reactions of beta-oxygenated methyl ketones.

被引：154

作者：

Paterson, I

Gibson, KR

Oballa, RM

机构：

[1] University Chemical Laboratory, Cambridge CB2 1EW, Lensfield Road

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 47期

关键词：

D O I：

10.1016/0040-4039(96)01962-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

High levels of 1,5-stereoinduction are obtained in the boron-mediated aldol reactions of beta-oxygenated methyl ketones 5, 7 and 8 with achiral aldehydes. The aldol products undergo stereoselective reductions, providing an efficient method of accessing a wide range of 1,3-polyols. Copyright (C) 1996 Elsevier Science Ltd

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页码：8585 / 8588

页数：4

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